公司名稱：南京康佰生物科技有限公司
地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
CBP61154LS513人盲腸癌細胞的詳細資料：
LS513人盲腸癌細胞
| CBP61154 | |
| I. General information | |
| Synonyms: | LS513 |
| Background: | LS513 is a colorectal carcinoma cell line isolated in 1985 from a primary tumor biopsy from a 63 year old Caucasian male patient diagnosed with a Dukes' C mucin secreting cecal tumor located at the Bauhin valve. |
| Species: | Homo sapiens, human |
| Tissue: | cecum |
| Disease: | Dukes' type C,colorectal carcinoma |
| Gender: | male， 63 years， Caucasian |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Doubling Time: | 25 hrs |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 10,13 D13S317: 9,10 D16S539: 12,13 D5S818: 9,11 D7S820: 8,11 THO1: 8 TPOX: 8 vWA: 16,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: | RPMI-1640+10%FBS We strongly suggest to purchase the complete medium from Cobioer. |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | carcinoembryonic antigen CEA; ICAM-1; HLA class I positive |
| Receptor Expression: | N/A |
| Karyotype | N/A |
| Virus Susceptibility | Vesicular stomatitis, Orsay Indiana Vesicular stomatitis, Glasgow Indiana Human poliovirus 1 |
| Oncogene: | p53 + wild type |
| Genes Expressed: | transforming growth factor beta 1 TGF beta-1, 83 pg per 106 cells per 24 hours |
| Cellular Products: | transforming growth factor beta 1 TGF beta-1, 83 pg per 10 exp6 cells per 24 hours |
| Tumor Formation: | Yes, forms tumors in nude mice |
| Comments: | LS513 is a colorectal carcinoma cell line isolated in 1985 from a primary tumor biopsy from a 63 year old Caucasian male patient diagnosed with a Dukes' C mucin secreting cecal tumor located at the Bauhin valve. Approximately 50% of LS513 cells express surface carcinoembryonic antigen CEA. LS513 cells express the major histocompatibility MHC class I antigens HLA and beta 2 microglobulin. MHC class II antigens HLA-DR, DQ, and DP were not detected. TGF beta-1 is inhibitory for proliferation of LS513 cells, whereas TGF beta-2 has no effect on the growth of these cells. LS513 cells are 100-fold less sensitive to TGF beta-1 than the LS1034 ATCC CRL-2158 cell line. LS513 cells are multidrug resistant MDR and are tumorigenic in nude mice. Colony forming efficiency was 30% in methylcellulose. For more information, please contact Cobioer 4008-750-250. |