公司名稱：南京康佰生物科技有限公司
地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
CBP73236c-Kit D820Y/BaF3的詳細資料：
CBP73236 | |
| I. Introduction | |
Cell Line Name： | c-Kit D820Y/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | |
Mycoplasma Status: | Negative |
| II.Background | |
KIT D820Y lies within the protein kinase domain of the Kit protein (UniProt.org). D820Yresuts in constitutive phosphorylation of Kit and is transforming in cell culture (PMID: 19035443, PMID: 11984533), and has also been identified as a secondary mutation associated with imatinib-resistance (PMID: 18488160). | |
| III. Representative Data | |
1. WB of c-Kit D820Y/BaF3 | |
2.Sanger of c-Kit D820Y/BaF3
| |
3. Anti-proliferation assay | |
Figure 2. CTG Proliferation Assay of BaF3 c-KIT D820Y (C1). | |
