公司名稱：南京康佰生物科技有限公司
地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
CBP60515NOMO-1人白血病細胞的詳細資料：
NOMO-1人白血病細胞
| CBP60515 | |
| I. General information | |
| Synonyms: | NOMO-1 |
| Background: | established from the bone marrow of a 31-year-old woman with acute myeloid leukemia AML FAB M5a at 2nd relapse; described in the literature to show strong lysozyme activity in the cytoplasm, phagocytic activities, and cells are responsive to induction of differentiation with TPA; cells carry the t9;11q23;p22 KMT2A-MLLT3 MLL-MLLT3; MLL-AF9 alteration |
| Species: | human Homo sapiens |
| Tissue: | N/A |
| Disease: | acute myeloid leukemia |
| Gender: | N/A |
| Morphology: | single round cells growing in suspension; |
| Growth Mode: | N/A |
| Doubling Time: | ca. 35 hours |
| DNA Profile: | N/A Cobioer’s Cell Line Authentication Service |
| Culture Medium: | RPMI1640+10%FBS We strongly suggest to purchase the complete medium from Cobioer. |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Mycoplasma: | negative in microbiological culture, PCR assays |
| Immunology: | CD3 -, CD4 +, CD13 +, CD14 -, CD15 +, CD19 -, CD33 +, CD34 -, HLA-DR +; image |
| Fingerprint: | multiplex PCR of minisatellite markers revealed a unique DNA profile |
| Species: | confirmed as human by cytogenetics |
| Cytogenetics: | human hyperdiploid karyotype with 8% polyploidy - 46-47<2n>XX, +8, -13, +mar, add7q32, der9del9p11p13-21t9;11p22;q23, t9;13q13;q11, der11t9;11p22;q23 - carries reciprocal t9;11 with rearrangement of KMT2A MLL - matches published karyotype |
| Molec. Genetics: | expression of fusion gene KMT2A-MLLT3 MLL-MLLT3; MLL-AF9 confirmed by RT-PCR |
| Virus | PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/II -, MLV -, SMRV - |
| Comments: | For more information, please contact Cobioer 4008-750-250. |