地址:南京市雨花區長虹路222號
郵編：
電話：025-86880024
手機: 18066071954
聯系人: 蔣
傳真：
E-mail: duhaitao@cobioer.com
CBP73110Her2 WT/BaF3激酶的詳細資料：
Her2 WT/BaF3激酶 CBP73110 | |
| I. Introduction | |
Cell Line Name： | Her2 WT/BaF3 |
Gene Synonyms: | NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu |
Host Cell: | Ba/F3 |
| Stability: | 16 passages |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10% FBS |
Mycoplasma Status: | Negative |
| II.Background | |
ERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238). | |
| III. Representative Data | |
1. WB of Her2 WT/BaF3
| |
2. Anti-proliferation assay | |
| |
Figure 2. Anti-proliferation assay of two reference compounds on the Ba/F3_HER2 WT Stable Cell line. | |
